Preventing Chemotherapy-Induced Metastasis in Breast Cancer

Chemotherapy is effective in treating invasive breast cancer. But can it also cause metastasis? Experimental studies in mice have suggested that this may be the case. In a further investigation of this matter, an international team of researchers has shown that two classes of chemotherapy drugs used in neoadjuvant (pre-operative) breast cancer therapy, taxanes and anthracyclines, cause tumors to release extracellular vesicles (EVs) such as exosomes that can enable the seeding and growth of metas...

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