Although survival in childhood acute lymphoblastic leukemia (ALL) has improved over the years, there remains a need to identify racial, ethnic, and socioeconomic health disparities that contribute to poor outcomes. In a study recently presented at the 63rd American Society of Hematology (ASH) Annual Meeting & Exposition, a team of researchers led by Dr. Sumit Gupta of the University of Toronto investigated the impact of race, ethnicity, and socioeconomic status among young patients with ALL enrolled in Children's Oncology Group studies between 2004 and 2019. The investigators identified significant disparities in survival outcomes in association with these factors. In this interview, Dr. Gupta explains the importance of recognizing health disparities among pediatric patients with ALL and the changes that can be implemented to address them.