Genetic Factor Discovered in Metastatic Prostate Cancer

Because prostate cancer cases are often localized and controlled, men can survive many years after diagnosis. However, that is not the case for metastatic castration-resistant prostate cancer (mCRPC): after diagnosis, less than a third of men survive five years. In the treatment of prostate cancer, hormone therapy is commonly used to suppress androgen receptors in order to prevent testosterone from being produced, thereby killing the malignant tumor. Unfortunately, this does not work for mCRPC. ...

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