Could Strawberry Tree Honey Fight Colon Cancer?

Researchers report that strawberry tree honey, a typical food in the Mediterranean region, has cancer-fighting potential in colon adenocarcinoma, the most common form of colorectal cancer. For the study, which has now been published in the Journal of Functional Foods, the investigators researched both the phytochemical composition and the anticancer effects of honey from the strawberry tree (Arbutus unedo) on cellular proliferation, cell cycle, and apoptosis—programmed cell death—in two types of...
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Trastuzumab Biosimilar Approved for Breast Cancer

Trastuzumab-pkrb (Herzuma®, Celltrion Inc.) has recently been FDA-approved to treat human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer. Trastuzumab-pkrb is a biosimilar to trastuzumab (Herceptin®, Genentech Inc.). Biosimilars—biological agents made from living organisms—are almost identical to another biological agent that has already been FDA-approved, known as the reference drug. Biosimilars and their reference drugs may differ in production and composition; however, ...
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Talazoparib Approved: Advanced HER2-Negative Breast Cancer With gBRCA Mutations

​Talazoparib (Talzenna®, Pfizer Inc.), an orally available poly (ADP-ribose) polymerase (PARP) inhibitor, has been approved by the United States Food and Drug Administration (FDA) for the treatment of patients with HER2-negative locally advanced or metastatic breast cancer with known or suspected deleterious germline BRCA (gBRCA) mutations. Eligibility for talazoparib therapy must be determined using the BRACAnalysis CDx® test (Myriad Genetic Laboratories Inc.), which the FDA has also approved a...
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