Preparing Nurses to Manage CAR T-Cell Therapy Adverse Events With Lindsey Bashaw, RN

Chimeric antigen receptor (CAR) T-cell therapy is a new form of immunotherapy in which a patient's own T cells are collected and genetically altered to target cancer cells. Although CAR T-cell therapy has shown encouraging clinical trial results in patients with acute lymphoblastic leukemia and B-cell lymphomas, they are associated with severe adverse events such as cytokine release syndrome, neurotoxicity, tumor lysis syndrome, and graft-versus-host disease. Many of the patients who receive CAR...

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