Oncology Data Advisor™ · Applying Precision Medicine in BRAF V600E-Mutant Metastatic Colorectal Cancer Colorectal cancer is the second leading cause of cancer death among men and women in the United States (ACS,2021). An estimated 149,500 new cases are diagnosed annually, and 52,980 people die of the disease (ACS, 2021). When detected and treated early at a localized stage, the 5-year survival rate is 90%. However, because colorectal cancer initially exhibits no symptoms and the use...

The old model of cancer treatments consisted of administering nonspecific cytotoxic therapies to various cancer patients. Now, cancer treatment has evolved to include agents that target a patient's genome and immune system, resulting in better patient outcomes. This 'precision medicine' approach individualizes treatment depending on each patient's unique tumor. Researchers discovered that using precision medicine to select combination treatments that target more than one genomic alteration is ef...