A Reference Point for Cancer Patients’ Quality of Life

Assessing health-related quality of life is essential to evaluating patients' wellbeing before, during, and after cancer treatment; it is also important for researchers determining the efficacy and side effects of new therapies. Without a norm to which data can be compared, however, such assessments are of limited use. Researchers from Charité - Universitätsmedizin Berlin have remedied this situation for one commonly used quality of life measure, obtaining normative data from the general populat...
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US Cancer Deaths Have Dropped 27% Over 25 Years

Although cancer is still the second leading cause of death after heart disease for both men and women, its overall lethality has nonetheless diminished steadily and significantly thanks to the progress of research. In its newly released annual report on cancer statistics, the American Cancer Society found that cancer death rates in the United States dropped continuously from 1991 to 2016 by a total of 27%. The authors of the report, published in CA: A Cancer Journal for Clinicians, note that thi...
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New Biomarkers Offer Treatment Clues for Prostate Cancer

Most often, men diagnosed with prostate cancer have a low risk of progression (LRP). However, some men have intermediate or high risk of progression (IHRP). Physicians tend to overtreat or undertreat patients because they do not have a reliable way to accurately determine the risk of progression. A new study published in Mayo Clinic Proceedings has provided a potential solution to this dilemma. "We have discovered new molecular markers that can help guide men in their decisions about the course ...
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Low Sugar Level Helps Virus Attack Cancer

Oncolytic viruses have the capability to attack malignant tumors without damaging the adjacent healthy cells. First, the virus invades the cancer cells; then, it multiplies, ultimately destroying the malignancies. Clinical trials are underway to determine the efficacy of oncolytic viruses in cancer treatment. In the laboratory, cancer cells are typically preserved in high temperatures and on diets of their energy source: sugar. However, in a study published in Cancer Research, scientists propose...
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Nanoscale Liquid Biopsy Technique Reveals More About Cancer

Something intriguing occurs when nanoparticles come into contact with biological fluids: proteins attach themselves to the nanoparticle surfaces, forming what is called a "protein corona." This phenomenon has now resulted in a technique that could allow doctors and researchers to glean additional information from the blood of cancer patients. When researchers from the University of Manchester extracted injected liposomes—lipid-based nanoparticles used for drug delivery with minimal side effects—...
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